As we age, many of us acquire mutations that cause some of our blood stem cells to multiply faster than others, forming their own distinct populations or "clones." This is known as clonal hematopoiesis. In some cases, a single ...
Nov 4, 2021
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Radiation can be a powerful cancer therapy, but it doesn't work for everyone. A new study identifies tumor features linked with resistance to radiotherapy, an important advance toward developing individualized cancer treatments.
Nov 3, 2021
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A team of investigators has discovered that the underexpression of a specific metabolic enzyme is a common and adverse epigenetic modulating feature in clear cell renal cell carcinoma (ccRCC), according to a recent study ...
Oct 21, 2021
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T-cells respond to buildups of alpha-synuclein, the aggregated protein clumps that are a feature of neurodegenerative diseases including dementia with Lewy bodies and Parkinson's disease (PD), according to a Northwestern ...
Oct 15, 2021
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For the first time, DNA mutations in liver cells have been identified that impact metabolism and insulin sensitivity in patients with liver disease. These mutations are specific to liver disease that is associated with obesity, ...
Oct 13, 2021
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Researchers have discovered a battle waged within the blood systems of children who inherit mutations in the genes SAMD9 and SAMD9L. The outcomes have life-or-death consequences for patients. Investigators are working to ...
Oct 7, 2021
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Huntington's disease is a fatal condition involving the death of brain cells, typically striking in midlife. But new findings suggest the disease process starts decades earlier. Although symptoms emerge in adulthood, researchers ...
Oct 5, 2021
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A team led by researchers at Weill Cornell Medicine, the New York Genome Center, Harvard Medical School, Massachusetts General Hospital and the Broad Institute of MIT and Harvard has profiled in unprecedented detail ...
Oct 1, 2021
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New research exploring theories of aging has found that small mutations accumulating in DNA are unlikely to be fully responsible for this process.
Oct 1, 2021
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A nationwide team of researchers, led by scientists at University of Utah Health and The Rockefeller University, has determined how a genetic mutation found in mice and monkeys interferes with viruses such as HIV and Ebola. ...
Sep 30, 2021
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