A stem cell transplant—also called a bone marrow transplant—is a common treatment for blood cancers, such as acute myeloid leukemia (AML). Such treatment can cure blood cancers but also can lead to life-threatening complications, ...
Jan 15, 2020
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107
Cancers are often made up of many cells which vary genetically to each other. These genetic differences mean the cancer may be particularly susceptible or resistant to a given treatment. As a result, identifying these variations ...
Jan 10, 2020
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22
Researchers at the University of Kentucky's College of Medicine have found that a class of antibiotics called aminoglycosides could be a promising treatment for frontotemporal dementia.
Jan 10, 2020
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220
Scientists at Rutgers University-Newark have discovered that when a key protein needed to generate new brain cells during prenatal and early childhood development is missing, part of the brain goes haywire—causing an imbalance ...
Jan 9, 2020
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507
As an embryo develops, its cells must learn what to do with the thousands of genes they've been equipped with. That's why each cell comes with a detailed gene-expression manual outlining exactly which genes should be switched ...
Dec 18, 2019
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39
Mount Sinai researchers have found that different mutations in a single gene can have myriad effects on a person's health, suggesting that gene therapies may need to do more than just replenish the missing or dysfunctional ...
Dec 18, 2019
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36
A common mutation in a key enzyme involved in alcohol metabolism increases damage in cells from patients with Alzheimer's disease and in mice, according to a study by researchers at the Stanford University School of Medicine.
Dec 11, 2019
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15408
Scientists from Australia and the US have discovered and identified the genetic cause of a previously unknown human autoinflammatory disease.
Dec 11, 2019
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707
Cystic fibrosis is caused by an inherited mutation in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. Due to this mutation, the CFTR protein doesn't embed in cell membranes to form a channel for chlorine ...
Dec 10, 2019
0
79
Duke Cancer Institute researchers have observed how stem cell mutations quietly arise and spread throughout a widening field of the colon until they eventually predominate and become a malignancy.
Dec 2, 2019
0
82
