Researchers at the University of California San Diego have uncovered a connection between the topography of the human genome and the presence of mutations in human cancer. They found that certain regions of the genome, which ...
Aug 24, 2023
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Duchenne muscular dystrophy (DMD) is a muscle degeneration disorder caused by mutations affecting the dystrophin gene. On August 24 in the journal Stem Cell Reports, researchers show how a dual CRISPR RNA method restored ...
Aug 24, 2023
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Researchers at The University of Texas MD Anderson Cancer Center have uncovered a functional role for KRAS mutations in pancreatic cancer and rapidly translated these findings into a novel therapeutic approach combining a ...
Aug 24, 2023
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A technique that enables scientists to record gene mutations and patterns of gene activity in individual cells has been extended to cover RNA splicing as well, in a study led by researchers at Weill Cornell Medicine, the ...
Aug 14, 2023
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Researchers at the Francis Crick Institute and UCL Queen Square Institute of Neurology, working with technology company Faculty AI, have shown that machine learning can accurately predict subtypes of Parkinson's disease using ...
Aug 10, 2023
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Researchers at Uppsala university have developed a new method to find mutations in brain tumors in children. They also showed that the mutations change how cancer cells respond to a cancer drug. These findings could lead ...
Aug 7, 2023
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Mutations in a genetic region that regulates RNA stability could influence prostate cancer outcomes and drug resistance, according to new work from scientists at Fred Hutchinson Cancer Center published in Cell Reports.
Aug 7, 2023
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The role played by mutations in the LRRK2 gene in promoting Parkinson's disease has long intrigued scientists, and even led to an experimental drug that inhibits the over-active protein. Yet exactly how LRRK2 triggers this ...
Jul 26, 2023
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Hematopoietic stem cells (HSCs) are rare cells found in the bone marrow that produce red blood cells, white blood cells, and platelets. Their correct functioning is indispensable for the growth and health of an organism. ...
Jul 10, 2023
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Scientists at St. Jude Children's Research Hospital created a hepatoblastoma (liver cancer) model that more accurately reflects the pathology and genomics of the disease. Research using the model pointed toward potential ...
Jul 7, 2023
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