Desperate for nutrients, rapidly growing pancreatic tumors resort to scavenging "fuel" through an alternative supply route, called macropinocytosis. Scientists are hopeful that blocking this process, often described as "cellular ...
Jun 27, 2019
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The early development of embryos is not well understood. One necessary stage is the formation of the blastocyst, a collection of cells present by about 4 days after fertilization of the egg, before implantation in the uterus. ...
Jun 27, 2019
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About one of every five breast cancers presents with high levels of HER2 proteins. Known as HER2-positive breast cancer, these tumors typically show an aggressive behavior—a greater likelihood of metastasis and relapse ...
Jun 25, 2019
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Usually, scientists study the molecular biology of cancer to find new treatments, but sometimes, it is the other way around: When seeking new treatments, scientists find key information on cancer biology. The researchers ...
Jun 13, 2019
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Many chemotherapy drugs kill cancer cells by severely damaging their DNA. However, some tumors can withstand this damage by relying on a DNA repair pathway that not only allows them to survive, but also introduces mutations ...
Jun 6, 2019
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In 2012, a pair of neurosurgery residents traded their scrubs for lab coats in an effort to understand, at the most basic level, what causes medulloblastoma, the most common pediatric brain cancer.
May 20, 2019
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A pair of collaborative studies led by Fen-Biao Gao, Ph.D., have identified two potential drug targets for the diseases amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). The studies, which appear in Nature ...
May 15, 2019
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A study at The University of Texas MD Anderson Cancer Center demonstrated how a small molecule drug discovered at the institution may help overcome resistance to treatment with ibrutinib in patients with mantle cell lymphoma.
May 8, 2019
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New research by Swansea University academics has shown that harnessing metabolism at a cellular level may help to relieve or heal a range of disorders.
May 7, 2019
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A discovery opens the possibility of one day restoring loss of vision by activating the retina's ability to regenerate. Researchers at Baylor College of Medicine, the Cardiovascular Research Institute and the Texas Heart ...
May 7, 2019
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