Medical research

Scientists develop new gene therapy strategy to delay aging

Cellular senescence, a state of permanent growth arrest, has emerged as a hallmark and fundamental driver of organismal aging. It is regulated by both genetic and epigenetic factors. Despite a few previously reported aging-associated ...

Medical research

Researchers provide novel insights into human skin aging

In human, the skin is one of the organs that exhibit early-onset aging-associated dysfunction. As a critical physical barrier, the skin is composed of a variety of cell types including fibroblasts and keratinocytes. Due to ...

Health

Why do older people heal more slowly?

I recently visited an 83-year-old patient in the hospital after EMTs rushed her to the ER with an infected leg wound. Her ordeal started inconspicuously when she bumped into the sharp edge of a table and developed a small ...

Medical research

Chronic inflammation causes a reduction in NAD+

NAD+ (nicotinamide adenine dinucleotide), a key metabolite central to an efficient and healthy metabolism, declines with age. This previously unexplained phenomena is associated with numerous age-related diseases and has ...

Medical research

Senescent cells may be good when it comes to a bad injury

It's called senescence, when stressed cells can no longer divide to make new cells, and it's considered a factor in aging and in some diseases. Now scientists have some of the first evidence that at a younger age at least, ...

Medical research

Rejuvenating old organs could increase donor pool

Despite the limited supply of organs available for patients on waitlists for transplantation, organs from older, deceased donors are frequently discarded or not utilized. Available older organs have the potential to close ...

Cardiology

Promising discovery for patients with diabetic retinopathy

Published in the journal Science, a new study has shed light on a cellular process that occurs in the retinas of people with diabetic retinopathy. This discovery could lead to the development of a treatment for this serious ...

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