As cells age and stop dividing, their fat content changes, along with the way they produce and break down fat and other molecules classified as lipids, according to a new University at Buffalo study.
Jan 19, 2017
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Atherosclerosis is a disease in which arteries narrow due to plaques. That narrowing can lead to heart attacks and strokes—both of which are leading causes of death in the U.S. Now, in a paper published in Science, Mayo ...
Oct 27, 2016
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New research shows that a cellular program that causes aging can also bring unexpected benefits in the function of pancreatic beta cells and the production of insulin in mice and humans. The findings are reported in the journal ...
Mar 7, 2016
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Chronic inflammation, closely associated with frailty and age-related diseases, is a hallmark of aging. Mayo Clinic researchers have discovered that inhibiting key enzyme pathways reduces inflammation in human cells in culture ...
Nov 2, 2015
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(Medical Xpress)—A team of researchers from Harvard Medical School and Buck Institute for Research on Aging has conducted a study that has revealed that GATA4 (a transcription factor) plays a significant role in cell senescence. ...
Intermittent dosing with rapamycin selectively breaks the cascade of inflammatory events that follow cellular senescence, a phenomena in which cells cease to divide in response to DNA damaging agents, including many chemotherapies. ...
Jul 6, 2015
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A research team from The Scripps Research Institute (TSRI), Mayo Clinic and other institutions has identified a new class of drugs that in animal models dramatically slows the aging process—alleviating symptoms of frailty, ...
Mar 9, 2015
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Changes to the structure of the protein histone H3.3 may play a key role in silencing genes that regulate cancer cell growth, according to a study led by researchers from the Icahn School of Medicine at Mount Sinai and published ...
Nov 21, 2014
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(Medical Xpress)—One way cells promote tumor suppression is through a process called senescence, an irreversible arrest of proliferation. Senescence is thought to be associated with normal aging, but is also a protective ...
Aug 30, 2013
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Researchers at Newcastle University have revealed the mechanism by which neurons, the nerve cells in the brain and other parts of the body, age. The research, published today in Aging Cell, opens up new avenues of understanding ...
Sep 12, 2012
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