Autosomal dominant polycystic kidney disease (ADPKD), the most common form of polycystic kidney disease, can lead to kidney enlargement and eventual loss of function. The disease affects more than 12 million people worldwide, ...
Jan 22, 2024
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Excessive alcohol intake is strongly associated with alcohol-associated liver disease (ALD) which accounts for 25% and 30% of deaths from cirrhosis and hepatocellular carcinoma. Impairment of Ca2+ influx and Ca2+-mediated ...
Jan 17, 2024
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Lifestyle and genetics, and a range of other factors within and outside our control, are known to contribute to development of metabolic syndrome, a cluster of conditions that add up to increased risk for serious health problems.
Jan 12, 2024
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During oxidative stress, excess production of reactive oxygen species causes cell and tissue damage.
Dec 21, 2023
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Major depressive disorder affects 16.1 million adults in the United States and costs $210 billion annually. While the primary symptoms of depression are psychological, scientists and doctors have come to understand that depression ...
Dec 15, 2023
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A new study identifies alterations in the transcriptomic signatures in human olfactory mucosal cells of individuals with Alzheimer's disease following SARS-CoV-2 infection, potentially contributing to exacerbated COVID-19 ...
Dec 15, 2023
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Late December is typically a time when holiday stress and winter weather can collide, creating a perfect recipe for a rise in heart attacks and stroke.
Dec 12, 2023
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A partnership between ophthalmology researchers at the University of Colorado School of Medicine and Johns Hopkins University expands the understanding of how oxidative stress contributes to the development of choroidal neovascularization ...
Dec 7, 2023
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In people with Alzheimer's disease (AD), the epigenetic regulator HDAC6 (histone deacetylase 6), which controls many biological processes, is significantly overexpressed in the brain.
Nov 27, 2023
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Researchers at the Francis Crick Institute have found that cellular structures called stress granules perform an essential protective function in support of the immune response against infections like tuberculosis (TB).
Nov 21, 2023
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