Neuroscience

Prying open the black box of the brain

The human brain is the most complex biological structure on Earth. It has about 100 billion neurons—each of which has thousands of connections to other neurons.

Parkinson's & Movement disorders

How disease mutations affect the Parkin protein

Researchers at the MRC Laboratory of Molecular Biology in the United Kingdom have determined the crystal structure of Parkin, a protein found in cells that when mutated can lead to a hereditary form of Parkinson's disease. ...

Alzheimer's disease & dementia

Scientists identify molecular trigger for Alzheimer's disease

Researchers have pinpointed a catalytic trigger for the onset of Alzheimer's disease – when the fundamental structure of a protein molecule changes to cause a chain reaction that leads to the death of neurons in the brain.

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