Oncology & Cancer

How breast cancer cells sneak past local immune defenses

Cold Spring Harbor Laboratory (CSHL) Associate Professor Mikala Egeblad and her colleagues describe a newly understood way by which breast cancer cells sabotage a key player in the body's immune system. That key player provides ...

Medical research

New opportunity for cancer drug development

After years of research on cell surface receptors called Frizzleds, researchers at Karolinska Institutet in Sweden provide the proof-of-principle that these receptors are druggable by small molecules. The results, which are ...

Immunology

How immune cells switch to attack mode

Macrophages have two faces: In healthy tissue, they perform important tasks and support their environment. However during an infection, they stop this work and hunt down pathogens instead. Upon coming into contact with bacteria ...

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