Research at UC San Francisco has shown for the first time how the commonly prescribed seizure and pain medication, gabapentin, acts inside of cells, opening the door to new, more effective treatments for diseases like epilepsy ...
May 31, 2023
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An experimental "decoy" has provided long-term protection from infection by the pandemic virus in mice, a new study finds.
May 30, 2023
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The MGAT5 glycosylation enzyme plays a crucial role in brain development, according to a study by University of California, Irvine researchers, a discovery that may contribute to new therapeutic purposes for neural stem cells.
May 16, 2023
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Cachexia is a syndrome characterized by severe loss of weight and muscle mass. It is present in approximately half of all lung cancer patients and is particularly damaging in cases of non-small cell lung cancer. Early detection ...
May 10, 2023
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What makes some cancer cells stay put while others break loose and spread through the body? A new study of C. elegans worms may hold some clues. Researchers at Duke University have put together what they say is the first ...
May 4, 2023
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The human body naturally produces opioid-like substances, such as endorphins, that block the perception of pain and increase the feeling of well-being. Similarly, opioid drugs, including morphine or fentanyl, are widely used ...
Apr 19, 2023
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Adding mint flavor to e-cigarette liquids produces more vapor particles and is associated with worse lung function in those who smoke, report researchers from the University of Pittsburgh in Respiratory Research today.
Apr 10, 2023
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The number of immune cells in and around kidney tumors, the amount of dead cancer tissue, and mutations to a tumor suppressor gene called PBRM1 form a biomarker signature that can predict—before treatment begins—how well ...
Apr 6, 2023
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A new study lead by a team of researchers at the Keck School of Medicine of USC shows that younger "brain age," a neuroimaging-based assessment of global brain health, is associated with better post-stroke outcomes. The findings ...
Apr 6, 2023
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In July 1969, Neil Armstrong became the first astronaut to walk on the moon. The Apollo 11 mission lasted about four days. Now more than 50 years later, astronauts are making much longer trips into space and looking ahead ...
Apr 5, 2023
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In biochemistry, a receptor is a protein molecule, embedded in either the plasma membrane or cytoplasm of a cell, to which a mobile signaling (or "signal") molecule may attach. A molecule which binds to a receptor is called a "ligand," and may be a peptide (such as a neurotransmitter), a hormone, a pharmaceutical drug, or a toxin, and when such binding occurs, the receptor undergoes a conformational change which ordinarily initiates a cellular response. However, some ligands merely block receptors without inducing any response (e.g. antagonists). Ligand-induced changes in receptors result in physiological changes which constitute the biological activity of the ligands.
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