Researchers at Children's Hospital of Philadelphia (CHOP) have identified variants of a chaperone molecule that optimizes the binding and presentation of foreign antigens across the human population, a finding that could ...
Feb 24, 2023
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The human immune system is a thing of wonder. Up until now it had been widely assumed that the ability of killer T cells to destroy tumor cells and pathogens would deteriorate with age. It turns out, however, that the opposite ...
Sep 21, 2022
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Arteriosclerosis bears great similarities to autoimmune diseases. Researchers from Leiden University show this in a new study they published in the journal Nature Cardiovascular Research. "This discovery suggests that treatment ...
Jan 31, 2023
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More than 15% of all critically ill patients who end up in intensive care with severe influenza or COVID-19 additionally develop aspergillosis, a pulmonary fungal infection. This doubles their mortality rate. A UZ Leuven ...
Aug 25, 2022
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Scientists at Nottingham Trent University and John Hopkins Kimmel Cancer Center in the U.S. found that as a result patients with acute myeloid leukemia (AML) are often unlikely to respond to treatment.
Nov 29, 2022
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Cancer immunotherapy drugs called PD-1 inhibitors are widely used to stimulate the immune system to fight cancer, but many patients either don't respond or develop resistance to them. A new small-molecule drug candidate being ...
Oct 4, 2023
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For many patients with a condition that often precedes multiple myeloma, early treatment can slow or delay the progression to myeloma. In a new study, investigators at Dana-Farber Cancer Institute demonstrate that changes ...
Nov 14, 2022
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Throughout the course of antiretroviral therapy, HIV hides quietly in reservoirs inside CD4+ T lymphocytes, white blood cells that play a role in activating the immune system against infection.
Jun 20, 2023
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For the first time, scientists have used CRISPR technology to insert genes that allow immune cells to focus their attack on cancer cells, potentially leaving normal cells unharmed and increasing the effectiveness of immunotherapy. ...
Nov 10, 2022
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Researchers at the University of Colorado Anschutz Medical Campus have discovered a drug combination that may offer a better prognosis for children diagnosed with MYC amplified Medulloblastoma, an often deadly form of brain ...
Jan 16, 2023
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