Oncology & Cancer

Putting the STING into cancer immunotherapy

Immune checkpoint blockade therapies have been revolutionary in the treatment of some cancer types, emerging as one of the most promising treatments for diseases such as melanoma, colon cancer and non-small cell lung cancer.

Immunology

Engineered bacteria find tumors, then alert immune cells

Combining discoveries in cancer immunology with sophisticated genetic engineering, Columbia University researchers have created a sort of "bacterial suicide squad" that targets tumors, attracting the host's own immune cells ...

Arthritis & Rheumatism

World's first CAR-T cell therapy for a child with lupus

In June 2023, Uresa A. (who was 15 years old at the time) received CAR-T cells at Universitätsklinikum Erlangen. The treatment was the last resort to slow down systemic lupus erythematosus (SLE), which is a serious autoimmune ...

Genetics

Epigenetic emergency switch improves defense against infections

During infections, the hematopoietic system switches from normal to emergency mode. This improves the defense against pathogens. Scientists at the German Cancer Research Center have now found an epigenetic switch in blood ...

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