Genetics

3D genome architecture influences SCID-X1 gene therapy success

Patients with X-linked severe combined immunodeficiency disorder (SCID-X1), sometimes called "bubble boy disease," are born with a defective gene that prevents them from producing immune cells. Gene therapy from St. Jude ...

Neuroscience

Regenerative cell therapy for epilepsy

Together with colleagues, veterinarian and neuroscientist Sonja Bröer has researched how regenerative cell therapies can contribute to curing or alleviating epilepsy. The work was carried out at biotechnology start-up Neurona ...

Oncology & Cancer

An ancient anti-cancer mechanism: DISE

A new editorial paper titled "DISE, an ancient anti-cancer mechanism that senses mutational load in cancerous cells?" has been published in Oncotarget.

Immunology

Making immunotherapy safe for AML

Acute myeloid leukemia (AML), the second most common leukemia in children, is hard to treat and has a five-year survival rate of just 65 to 70%, according to the American Cancer Society. While immunotherapies like monoclonal ...

Oncology & Cancer

Q&A: Merkel cell carcinoma

I recently heard about a type of skin cancer called Merkel cell carcinoma. I'm not familiar with this condition. Can you explain what it is? Do I need to do anything different to protect myself?

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