CAR-T cell therapy is a safe and effective treatment for diffuse large B-cell lymphoma (DLBCL), even for patients regarded as high risk due to comorbidities.
Dec 11, 2023
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The Malaghan Institute of Medical Research, in collaboration with Wellington Zhaotai Therapies Limited, today announced results of its phase 1 dose escalation trial of a new third generation anti-CD19 chimeric antigen receptor ...
Dec 11, 2023
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Patients with sickle cell disease (SCD) often face a reduced quality of life and a lower life expectancy. Allotransplantation, the first treatment for SCD with curative potential, comes with risks, including transplant-related ...
Dec 11, 2023
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Early results from a Phase I clinical trial of AT101, a new CAR T cell therapy that uses a distinct binding mechanism to target CD19, show a 100% complete response (CR) rate at the higher dose levels studied in the trial, ...
Dec 11, 2023
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A study led by researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine suggests that CAR-T immunotherapy remains a viable option for patients who have lymphoma that goes into ...
Dec 10, 2023
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The United States on Friday approved a breakthrough therapy that uses revolutionary gene editing tool CRISPR to treat the debilitating blood disorder sickle cell disease.
Dec 8, 2023
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The Food and Drug Administration announced last week that it's investigating reports of secondary cancers in patients who received CAR T-cell therapy, one of a suite of immunotherapies that have revolutionized cancer care ...
Dec 8, 2023
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The Food and Drug Administration is expected to decide by Dec. 8 on a new therapy to treat sickle cell disease using gene editing technology called CRISPR, which stands for clustered regularly interspaced short palindromic ...
Dec 8, 2023
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Researchers at TU Delft designed novel 3D-engineered scaffolds inspired by the geometry of the brain microvasculature. The micro-structures were co-cultured with both glioblastoma, an aggressive brain cancer, and endothelial ...
Dec 8, 2023
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Indiana University School of Medicine researchers have uncovered vital insights regarding a liver trigger that blocks an undesired immune response from gene therapy, surprisingly resulting in activating specific immune cells ...
Dec 7, 2023
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