Oncology & Cancer

Why don't T cells destroy solid tumors during immunotherapy?

The great hope of cancer immunotherapy is to bolster our own immune cells in specific ways to keep cancer cells from evading our immune system. Although much progress has been made, immunotherapy does not always work well. ...

Cardiology

Researchers develop myocardial infarction treatment patch

Myocardial infarction is an ischemic disease in which a coronary artery supplying blood to the heart muscle is stenotic or obstructed, resulting in cardiac tissue necrosis. Due to the irreversible loss of cardiomyocytes, ...

Oncology & Cancer

Examining resistance to immunotherapy in ovarian cancer

A team at Memorial Sloan Kettering Cancer Center (MSK) has uncovered several mechanisms of immune escape that can help explain why ovarian cancers have been resistant to immunotherapy to date.

Neuroscience

Why does the Alzheimer's brain become insulin-resistant?

As the population ages, the number of people with neurodegenerative diseases, such as Alzheimer's disease, increases. Approximately 75,000 Canadians are diagnosed with Alzheimer's disease each year and experience a decline ...

Medications

Study shows promise of new anti-KRAS drug for pancreatic cancer

A small molecule inhibitor that attacks the difficult to target, cancer-causing gene mutation KRAS, found in nearly 30 percent of all human tumors, successfully shrunk tumors or stopped cancer growth in preclinical models ...

Immunology

Common immune cells found to sometimes prevent intestinal healing

B cells are critical to the proper functioning of the immune system. However, researchers at Karolinska Institutet have shown that they can sometimes do more harm than good, as their numbers greatly increase after bowel damage, ...

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