Cardiology

MicroRNA molecule can cause pathological changes in the heart

Cardiac fibrosis involves an increase of connective tissue in the cardiac muscle, causing a loss of function. A team of researchers at the Technical University of Munich (TUM) has now discovered that microRNA 29 (miR-29) ...

Oncology & Cancer

Study links mutations in notch gene to role in B cell cancers

Notch is one of the most frequently mutated genes in chronic lymphocytic leukemia (CLL), the most common leukemia in adults in the United States. It is also often mutated in other common B cell tumors, such as mantle cell ...

Oncology & Cancer

New bowel cancer drug target discovered

Researchers at the Francis Crick Institute have discovered a new drug target for bowel cancer that is specific to tumour cells and therefore less toxic than conventional therapies.

Oncology & Cancer

A cancer therapy that inhibits the Notch signaling pathway

EPFL spin-off Cellestia Biotech has just been given the regulatory go-ahead to start clinical testing a molecule it has developed to treat cancers involving mutations of the Notch gene. The molecule is a ray of hope for the ...

Oncology & Cancer

New strategy against childhood cancer

Neuroblastoma is a cancer in children that originates in the sympathetic nervous system and has a high mortality. Current treatment includes chemotherapy and radiotherapy with their potentially severe side effects; there ...

Diabetes

Researchers implicate suspect in heart disease linked to diabetes

People with diabetes are at high risk of developing heart disease. Despite knowing this, scientists have struggled to trace the specific biology behind that risk or find ways to intervene. Now, UNC School of Medicine researchers ...

page 16 from 37