Diseases, Conditions, Syndromes

High iron, copper levels block brain-cell DNA repair

No one knows the cause of most cases of Alzheimer's, Parkinson's and other neurodegenerative disorders. But researchers have found that certain factors are consistently associated with these debilitating conditions. One is ...

Medical research

Simple urine test could measure how much our body has aged

Researchers find that a substance indicating oxidative damage increases in urine as people get older. The study, published today in open-access journal in Frontiers in Aging Neuroscience, also describes a way to easily measure ...

Oncology & Cancer

Researchers demonstrate why DNA breaks down in cancer cells

Damage to normal DNA is a hallmark of cancer cells. Although it had previously been known that damage to normal cells is caused by stress to their DNA replication when cancerous cells invade, the molecular basis for this ...

Immunology

Mitochondrial respiratory chain sustains inflammation

Northwestern Medicine investigators recently discovered that the mitochondrial respiratory chain—a series of protein complexes essential for a cellular respiration and energy production—is necessary for the activation ...

Immunology

Study pinpoints key pathway in inflammation and aging

In patients with colitis, a serious condition affecting the gut, the immune system turns against the body's own microbes, causing inflammation. To combat this inflammation, scientists have focused in on a chemical signal ...

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