Faulty DNA disposal system found to cause inflammation

Cells in the human body contain power-generating mitochondria, each with their own mtDNA—a unique set of genetic instructions entirely separate from the cell's nuclear DNA that mitochondria use to create life-giving energy. ...

Medical research

Researchers identify potential target in myeloid malignancies

Researchers at Children's Hospital of Philadelphia (CHOP) have identified a molecule that plays a role in post-translational modification and activation in myeloid malignancies, making it a potential therapeutic target. The ...

Inflammatory disorders

Study may explain why high-sugar diets can worsen IBD

Excess sugar hampers cells that renew the colon's lining in a mouse model of inflammatory bowel disease (IBD), according to a new study by University of Pittsburgh scientists.

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