When tendons get irritated it can lead to a serious condition called tendinosis—a common class of sports and workplace injuries—which is also common in older individuals. It can take many weeks of rest for tendon irritation ...
Apr 2, 2019
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The discovery of a 'switch' that modifies a gene known to be essential for normal heart development could explain variations in the severity of birth defects in children with DiGeorge syndrome.
Aug 23, 2012
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In people with Alzheimer's disease (AD), the epigenetic regulator HDAC6 (histone deacetylase 6), which controls many biological processes, is significantly overexpressed in the brain.
Nov 27, 2023
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The calcium ion Ca2+ regulates an enormous number of cellular processes. Control of Ca2+ is therefore crucial and is achieved by precise regulation of proteins that allow the ion to move between different parts of the cell. ...
Nov 14, 2014
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Research published Aug. 1 by scientists at Cold Spring Harbor Laboratory (CSHL) links gene mutations found in some patients with Meier-Gorlin syndrome (MGS) with specific cellular dysfunctions that are thought to give rise ...
Jul 31, 2012
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Researchers in Singapore are gaining further insight into how the mechanical environment of cells drives fundamental cellular processes such as motility, growth and survival. These processes are integral to many clinical ...
Mar 19, 2015
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As they work together to form body parts, cells in developing organisms communicate like workers at a construction site. The discovery of a new signaling molecule in flies by Brown University biologists not only helps explain ...
Apr 2, 2012
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The 18th century natural philosopher Jean-Baptiste Lamarck proposed that the necks of giraffes lengthened as a consequence of the cumulative effort, across generations, to reach leaves just out of their grasp. This view of ...
Feb 14, 2013
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There is growing evidence that the appearance and texture of the skin that is altered during the aging process are considerably enhanced by the accumulation of senescent dermal fibroblasts. These senescent cells magnify aging ...
Oct 31, 2022
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Melbourne researchers have made a major step forward in understanding how changes in an essential cellular process, called minor class splicing, may cause a severe developmental disease.
Feb 10, 2014
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