(Medical Xpress)—A University of Cincinnati (UC) cancer biology team reports breakthrough findings about specific cellular mechanisms that may help overcome endocrine (hormone) therapy-resistance in patients with estrogen-positive ...
Nov 2, 2012
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Researchers report in the journal Developmental Cell that they have identified genes that control growth and regeneration of the intestine in the freshwater planarian Schmidtea mediterranea.
Oct 25, 2012
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As outlined in a study published in Developmental Cell, researchers have discovered a novel function for p27 in the control of interneuron migration in the developing cerebral cortex.
Oct 2, 2012
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In the complex chain of molecular events that underlie eating behaviors and body weight, the AMP-activated protein kinase (AMPK) enzyme has proven to be a critical link.
Jul 3, 2012
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A new study identifies specific cell-stress signaling pathways that link injury of the optic nerve with irreversible vision loss. The research, published by Cell Press in the February 9 issue of the journal Neuron, may lead ...
Feb 8, 2012
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Scientists at the University of North Carolina at Chapel Hill School of Medicine have identified a cellular protein that plays a central role in the formation of new blood vessels. The molecule is the protein Shc (pronounced ...
Nov 28, 2011
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Whitehead Institute scientists have determined that master transcription factors determine the genes regulated by key signaling pathways. In this way, signaling pathways are targeted to genes that are most relevant to each ...
Oct 27, 2011
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Antineoplastic agents such as immunotherapies and targeted therapies that specifically target signaling pathways in cancer cells are associated with thyroid dysfunction in 20%-50% of cancer patients taking them, which can ...
Oct 18, 2011
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A new study from Mount Sinai School of Medicine has found that a cellular signaling pathway governs the differentiation of cells into fat tissue or smooth muscle, which lines the vascular system. Engaging this signaling pathway ...
Jun 14, 2011
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(Medical Xpress) -- In a new study, Yale University researchers have identified a pathway by which reactive oxygen species (ROS) molecules, which are usually implicated in the aging process due to their damage to DNA, can ...
Jun 8, 2011
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