Neuroscience

Biologists uncover details of how we squelch defective neurons

Biologists at the University of California, San Diego have identified a new component of the cellular mechanism by which humans and animals automatically check the quality of their nerve cells to assure they're working properly ...

Oncology & Cancer

Researchers investigate 59 tumor cell lines

In what is the biggest study of its kind to date, researchers from Technische Universität München (TUM) have identified over 10,000 different proteins in cancer cells. "Nearly all anti-tumor drugs are targeted against cellular ...

Oncology & Cancer

Breast CA nodal mets more common with certain mutations

(HealthDay)—Lymph node metastases are more common in breast cancers with mutations in a cellular signaling pathway associated with growth, according to a study published online July 24 in JAMA Surgery.

Medical research

Central signaling response found in mitochondrial energy diseases

Researchers have identified a master network of signaling molecules that acts like a "fuse box" to regulate the cellular effects of defective energy flow in mitochondrial respiratory chain diseases—a diverse set of difficult-to-treat ...

Genetics

Meet CLAMP: A newly found protein that regulates genes

(Medical Xpress)—A newly discovered protein, found in many species, turns out to be the missing link that allows a key regulatory complex to find and operate on the lone X chromosome of male fruit flies, bringing them to ...

Neuroscience

Researchers identify 'switch' for long-term memory

Neurobiologists at Heidelberg University have identified calcium in the cell nucleus to be a cellular "switch" responsible for the formation of long-term memory. Using the fruit fly Drosophila melanogaster as a model, the ...

Oncology & Cancer

Using computer models to predict more effective therapies

Scientist at Charité – Universitätsmedizin Berlin have used a computer simulation for predicting the effectiveness of various combination therapies for colon tumors. The study has been published in the current issue of ...

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