Alzheimer's disease & dementia

What happens in brain cells affected by Alzheimer's disease?

Affecting over 50 million people, Alzheimer's disease is the most common form of dementia and primarily occurs in people over the age of 65. The pathology of the disease in the brain is mainly characterized by two factors: ...

Medical research

Research sheds light on earliest stages of Angelman syndrome

New research from North Carolina State University provides insights into the earliest stages of Angelman syndrome. The work also demonstrates how human cerebral organoids can be used to shed light on genetic disorders that ...

Medications

Brain organoids with the potential to predict drug permeability

The human brain is bathed in a supportive fluid called the cerebrospinal fluid (CSF) that provides nutrients and is required for proper brain function. The composition of human CSF and how it is made are poorly understood ...

Neuroscience

Researchers grow active mini-brain-networks

Cerebral organoids are artificially grown, 3-D tissue cultures that resemble the human brain. Now, researchers from Japan report functional neural networks derived from these organoids in a study publishing June 27 in the ...

Neuroscience

Scientists develop 'mini-brain' model of human prion disease

National Institutes of Health scientists have used human skin cells to create what they believe is the first cerebral organoid system, or "mini-brain," for studying sporadic Creutzfeldt-Jakob disease (CJD). CJD is a fatal ...

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