Alzheimer's disease & dementia

Another angle on Alzheimer's: CSF, proteomics, and metabolic enzymes

Currently there are no objective, easily assessed diagnostic markers for Alzheimer's disease, and no good therapeutic options. Taking an agnostic approach, proteomics expert Hanno Steen, Ph.D., and neurobiologist Judith Steen, ...

Neuroscience

A key biological pathway for multiple sclerosis uncovered

Cross-talk between brain cells and peripheral immune cells can modulate the progression of multiple sclerosis (MS), Mount Sinai researchers have discovered. Their findings reveal a previously unknown way in which the brain ...

Neuroscience

Language impairment in autism associated with gray matter volume

Researchers from Russia and the U.S. have found language impairment in children with Autism Spectrum Disorder (ASD) to be associated with a lower volume of gray matter and greater gyrification in the temporal and frontal ...

Neuroscience

Fluid flow in the brain can be manipulated by sensory stimulation

Researchers at Boston University, U.S. report that the flow of cerebrospinal fluid in the brain is linked to waking brain activity. Led by Stephanie Williams, and publishing in the open access journal PLOS Biology on March ...

Neuroscience

Study reveals a driver of brain cell damage in neurodegeneration

Scientists have long known that the complement cascade, a set of immune system proteins, protects against infection in the body. But in recent years, researchers have uncovered new roles for the system in the brain, including ...

Medical research

Calcium: A key player for a promising and safe brain treatment?

A promising therapy for a range of brain diseases involves antisense oligonucleotides (ASOs)—specialized molecules that can modulate RNA and alter protein production—directly injected into the cerebrospinal fluid, in ...

Oncology & Cancer

Researchers develop liquid biopsy test for pediatric solid tumors

Pediatric solid tumors make up approximately 40% of all childhood cancers. While pediatric cancer is rare, children can develop a wide range of tumor types, located in different parts of the body, which can make the differential ...

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