UNSW medical researcher Dr. David Jacques and his team have discovered how the human immunodeficiency virus (HIV) breaches the cell nucleus to establish infection, a finding that has implications beyond HIV biology.
Jan 24, 2024
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Chaperone protein imbalance can play a significant role in initiating toxic accumulation of tau in the aging brain—an early step in the development of Alzheimer's disease and related neurodegenerative disorders known as ...
Apr 20, 2021
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A study led by scientists at the Institute for Research in Biomedicine (IRB Barcelona) and published in Nature Communications proposes chaperone protein Hps70 as an attractive therapeutic target for the treatment of Kennedy's ...
Aug 8, 2019
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Targeting a single protein can help fight both breast cancers and leukemias, according to two reports published online on January 23 in the Journal of Experimental Medicine.
Jan 23, 2012
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Chaperone proteins play an important role in protein folding in human cells and in bacteria and are promising new targets for drugs to treat cancer and Alzheimer's disease and for novel antiviral drugs and antibiotics. How ...
Mar 9, 2015
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A drug that indirectly impairs the function of several cancer-driving proteins, including anaplastic lymphoma kinase (ALK), may be an effective new treatment for patients with ALK—positive non-small cell lung cancer.
Mar 26, 2013
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"Who will watch the watchers?" asked Roman poet Juvenal way back in the first century C.E. Nature has been addressing that very question for much, much longer. The human body contains proteins that are designed to protect ...
Jul 12, 2024
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The cells of our immune system constantly communicate with one another by exchanging complex protein molecules. A team led by researchers from the Technical University of Munich (TUM) has now revealed how dedicated cellular ...
Sep 25, 2019
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A new drug can help advanced lung cancer patients live longer and may aid in treating other kinds of cancer, researchers said Monday.
Jun 3, 2013
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Scientists have discovered how special proteins in the blood prevent our immune system from harming our own cells with overproduced molecules.
Oct 19, 2021
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