Researchers in UC Santa Barbara neuroscientist Kenneth S. Kosik's lab have discovered a novel organelle—a previously unknown cell structure whose function it is to help clean up faulty proteins in times of stress and keep ...
Jun 14, 2022
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Alzheimer's disease is a progressive degenerative brain disease most commonly characterized by memory deficits. Loss of memory function, in particular, is known to be caused by neuronal damage arising from the misfolding ...
Jul 12, 2013
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Among the hallmarks of Alzheimer's disease are the Alzheimer fibrils, deposits of the tau protein, which accumulate in nerve cells in the form of fibres and disrupt communication between nerve cells. But how does this fibre ...
Mar 13, 2020
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While vaccination can provide life-saving protection against COVID-19, scientists are still searching for ways to treat severe infections, including in people who cannot get vaccinated or in the event that dangerous new strains ...
Nov 14, 2022
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Chaperone proteins in human cells dynamically interact with the protein α-Synuclein, which is strongly associated with Parkinson's disease. A disturbed relationship to these "bodyguards" leads to cell damage and the formation ...
Dec 4, 2019
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An immunological test known as a "tetramer assay" can detect and quantify the T cells in a blood sample that are able to recognize a specific antigen, such as a viral protein. Making the molecular probes needed for this type ...
Apr 20, 2020
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A new study published in Nature Communications gives insights into the underlying mechanisms of the formation of protein clumps in Alzheimer's disease. The study, led by researchers from Karolinska Institutet, could pave ...
Feb 2, 2024
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Groundbreaking new findings by UC Irvine and German chemists about how cataracts form could be used to help prevent the world's leading cause of blindness, which currently affects nearly 20 million people worldwide.
Dec 5, 2013
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Like pieces of tape that crumple, stick together, and can be turned into a ball, proteins that begin to lose their shape become sticky and tend to clump together. When this happens, rather than being transported to recycling ...
Jan 22, 2020
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In a new study, scientists at The Scripps Research Institute (TSRI) have identified drug candidates that can boost a cell's ability to catch the "typos" in protein production that can cause a deadly disease called amyloidosis.
Jul 20, 2016
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