The anti-tumor protein p53 can decide on the life or death of a cell: If it detects damage in the cell's genome, the protein pushes the cell to suicide. New research conducted at Technical University of Munich (TUM) shows ...
May 21, 2019
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Mutations in a gene involved in steroid signaling likely contribute to preterm birth, report Johanna Huusko of the University of Oulu and Cincinnati Children's Hospital Medical Center and colleagues, in a study of European ...
Jul 12, 2018
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A new study conducted by researchers at The Wistar Institute revealed how a key protein residing in the endoplasmic reticulum (ER) helps cells respond to stress. This process is especially important for B cells to respond ...
Mar 6, 2018
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Huntington's disease is a neurodegenerative disease. It is always fatal. The disease is caused by a defect in the Huntingtin gene. To this day, no therapy will put a stop to the insidious disintegration of brain cells. Fortunately, ...
Dec 12, 2017
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Scientists at the Max Planck Institute of Psychiatry in Munich have now identified a new functional link between the established depression risk factor FKBP51 and epigenetic changes. This new link improves our understanding ...
Nov 25, 2015
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University of Cincinnati (UC) researchers have observed levels of HAX-1, an anti-cell death protein, drop significantly in mice after a heart attack and during heart failure resulting in cardiac cells dying at a higher than ...
Nov 16, 2015
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A Kansas State University-led study is helping uncover the intricate workings of how a specific "molecular machine" inside of cells is assembled. Fully understanding this process may present new target sites for drugs and ...
Mar 16, 2015
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Chaperone proteins play an important role in protein folding in human cells and in bacteria and are promising new targets for drugs to treat cancer and Alzheimer's disease and for novel antiviral drugs and antibiotics. How ...
Mar 9, 2015
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Scientists at The Scripps Research Institute (TSRI) have identified a new cellular pathway that is affected in cystinosis, a rare genetic disorder that can result in eye and kidney damage.
Feb 10, 2015
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One of the hopes for victory against cancer hinges on naturally-occurring proteins whose job is to make their host cell die.
Feb 3, 2014
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