Alzheimer's disease & dementia

Molecular inhibitor breaks cycle that leads to Alzheimer's

A molecular chaperone has been found to inhibit a key stage in the development of Alzheimer's disease and break the toxic chain reaction that leads to the death of brain cells, a new study shows. The research provides an ...

Genetics

Even when you're older you need chaperones

Aging is the most significant and universal risk factor for developing neurodegenerative diseases, such as amyotrophic lateral sclerosis (ALS) and Alzheimer's, Parkinson's and Huntington's diseases. This risk increases disproportionately ...

Medical research

Study shows how misfolded proteins are selected for disposal

It's almost axiomatic that misfolded proteins compromise how cells normally function and cause debilitating human disease, but how these proteins are detected and degraded within the body is not well understood. Neurodegenerative ...

Neuroscience

Stress-related protein speeds progression of Alzheimer's disease

A stress-related protein genetically linked to depression, anxiety and other psychiatric disorders contributes to the acceleration of Alzheimer's disease, a new study led by researchers at the University of South Florida ...

Neuroscience

Researchers discover possible key to degenerative nerve diseases

(Medical Xpress) -- Researchers at the University of Wisconsin-Madison and collaborators have discovered a powerful new protein in the eye of the fruit fly that may shed light on blinding diseases and other sensory problems ...

Immunology

Shedding more light on how the body controls our immune systems

The membrane attack complex (MAC) is a set of proteins typically formed on the surface of pathogen cell membranes. They punch tiny holes in an invading bacteria's membrane. The bacteria ultimately dies if enough holes are ...

Health

Host-microbe interactions in the gut

Although the mutually beneficial relationship between human beings and gut microbes is clear, how we—the host—affect the functions of gut microbial communities remains poorly understood.

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