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US moves to block Purdue Pharma opioid settlement

The US Justice Department has challenged a plan that would dissolve Purdue Pharma, manufacturer of the OxyContin drug that has been blamed for the country's opioid crisis, while shielding its founders from lawsuits.

Medical research

Protein linked to intellectual disability has complex role

Fragile X syndrome, the leading inherited cause of intellectual disability, is due to a genetic mutation that largely eliminates the fragile X protein, a critical element of normal brain development and function.

Cardiology

Quantitative assessment of the blood coagulation cascade

Thrombosis is a harmful activation of the clotting process that prevents bleeding in healthy people. Thrombosis is associated with the occurrence of strokes, ischemic heart disease, and other blood vessel-related diseases. ...

Medical research

Engineers harness muscle power for healing

Bioengineers have developed biocompatible generators that create electrical pulses when compressed by body motions. The generators are made up of self-assembling "piezoelectric wafers" which can be made rapidly and inexpensively ...

Neuroscience

Rebuilding spinal cords with an engineer's toolkit

Like an earthquake that ruptures a road, traumatic spinal cord injuries render the body's neural highway impassable. To date, there are neither workable repairs nor detours that will restore signal flow between the brain ...

Neuroscience

Using pulsed magnetic fields to fight neurodegenerative diseases

In motor neuron diseases of the nervous system, such as amyotrophic lateral sclerosis (ALS), commands can no longer be sent to the muscles. This gradually leads to paralysis. Physicist Dr. Thomas Herrmannsdörfer from the ...

Diseases, Conditions, Syndromes

US approves dengue vaccine Dengvaxia

US health authorities have given their approval to dengue vaccine Dengvaxia, the controversial first treatment designed to protect against the deadly mosquito-borne virus.

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