Immune checkpoint inhibitors such as Keytruda and Opdivo work by unleashing the immune system's T cells to attack tumor cells. Their introduction a decade ago marked a major advance in cancer therapy, but only 10% to 30% ...
Nov 15, 2022
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Scientists have found at least one instance when the smaller sibling gets to call the shots and cancer patients may one day benefit.
Jan 3, 2012
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Immune checkpoint inhibitors have revolutionized cancer care. The therapy works by preventing tumors from shutting down the immune response, which in turn allows T cells to kill cancer cells. Established checkpoint inhibitors ...
Jun 27, 2022
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KAIST medical scientists have presented a novel pathways involving T immune cell exhaustion, providing evidence and rationale for designing optimal strategies for immune checkpoint blockades in cancer patients.
Dec 28, 2018
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During cell division, the duplicated DNA must be split equally between two identical 'daughter' cells. If this does not occur correctly, then health problems such as cancer can arise.
Apr 23, 2021
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In 1996, the technique known as somatic cell nuclear transfer (SCNT) transformed the idea of cloning from science fiction into reality. SCNT entails removing the nucleus from an adult somatic cell of the animal being cloned ...
Jun 1, 2012
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Researchers at the Terasaki Institute for Biomedical Innovation (TIBI) have developed and optimized a minimally invasive method for more targeted, efficient, and sustained delivery of immunotherapeutic treatments for cancer. ...
Aug 2, 2022
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A combination of two drugs that target different proteins on immune system T cells kept advanced melanoma in check significantly longer than one of the drugs alone in a phase 3 clinical trial involving 714 patients. Dana-Farber ...
May 20, 2021
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Researchers at the Department of Hepatology of Osaka City University Graduate School of Medicine introduced sorafenib to patients with advanced stages of the liver cancer hepatocellular carcinoma (HCC) and measured the amount ...
Mar 9, 2020
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Ludwig Maximilian University researchers have discovered that a protein which is well known for its role as a tumor suppressor is also required for inhibition of the replication of the coronavirus that causes SARS.
Aug 15, 2016
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