Cancer experts have tried, sometimes unsuccessfully, to use the total number of mutations in a tumor, called the tumor mutation burden (TMB), to predict a patient's response to immunotherapy. Now, investigators at the Johns ...
Jan 26, 2023
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A new study by researchers at The Ohio State University Comprehensive Cancer Center—Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC—James) suggests a way to re-energize critical killer ...
Jan 24, 2023
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Fibrotic cancers such as gastric cancers are highly resistant to conventional therapies like immune checkpoint inhibitors. Cancer-associated fibroblasts (CAFs) are an important part of the tumor microenvironment contributing ...
Jan 23, 2023
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Targeting cellular post-transcription mechanisms in the CD73 ectoenzyme may promote anti-tumor immunity and slow cancer progression in triple-negative breast cancer, according to a Northwestern Medicine study published in ...
Jan 19, 2023
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Immune checkpoint inhibitors are important medications that boost the immune system's response against various cancers, but some patients' cancer cells are unaffected by the drugs or develop resistance during treatment.
Jan 12, 2023
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Immunotherapy is a way of treating cancer by reprogramming the patient's immune system to attack their tumor. This cutting-edge approach has significantly impacted the treatment of cancer patients, and already boasts cases ...
Jan 10, 2023
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Nano-sized membrane bubbles known as extracellular vesicles activate the immune system in mice and seem to render their tumors sensitive to a type of immunotherapy drug called a checkpoint inhibitor. This is according to ...
Dec 22, 2022
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Researchers at Michigan Medicine have devised a new biomarker-based strategy to screen for a rare and deadly complication caused by monoclonal antibodies used to treat several cancers.
Dec 20, 2022
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Even as they've revolutionized cancer treatment, drugs known as immune checkpoint inhibitors can produce a range of adverse, immune-related side effects. In a new study, scientists at Dana-Farber Cancer Institute identify, ...
Dec 16, 2022
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Thanks to advances in cancer therapies, most forms of breast cancer are highly treatable, especially when caught early.
Dec 15, 2022
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