A recent study by Monash University has found that proteins found naturally in tick saliva, called evasins, can be modified to block the activity of important proteins in human inflammatory diseases such as arthritis, asthma ...
Feb 22, 2022
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Atherosclerosis, a lipid-triggered chronic inflammatory disease of the arteries, is the main cause of strokes and heart attacks. An international team of researchers led by the Technical University of Munich (TUM) and the ...
Feb 12, 2021
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Researchers from Boston University School of Medicine (BUSM) using a traditional Korean medicine, SO-CHEONG-RYONG-TANG (SCRT) that has long been used for the treatment of allergic diseases in Asia, found that SCRT treatment ...
Jun 30, 2011
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Observational epidemiologic studies relating wine and alcohol to health all suffer from the fact that they, of necessity, compare people who prefer certain beverages, but not the beverages themselves. While there have been ...
Jan 17, 2012
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(HealthDay)—A new vaccination approach may provide protection against genital herpes as well as other sexually transmitted infections, including HIV, according to a new study involving mice.
Oct 17, 2012
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(Medical Xpress)—Researchers at Moffitt Cancer Center have discovered a unique immune gene signature that can predict the presence of microscopic lymph node-like structures in metastatic melanoma. The presence of these ...
Oct 25, 2012
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(Medical Xpress)—A group of researchers in Austria and Switzerland has for the first time proven that immune cells migrate along chemical concentration gradients. This process has long been assumed but never demonstrated ...
Immune checkpoint inhibitors are important medications that boost the immune system's response against certain cancers; however, they tend to be ineffective against glioblastoma, the most deadly primary brain tumor in adults. ...
Dec 23, 2019
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Mast cells, which can help the body respond to bacteria and pathogens, also apparently sound the alarm around viruses delivered by a mosquito bite, according to researchers at Duke-NUS Graduate Medical School in Singapore.
May 16, 2011
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Researchers at the Medical College of Wisconsin have shown that a protein can inhibit metastasis of colon and melanoma cancers. The findings are published in the October 10, 2011 issue of Proceedings of the National Academy ...
Oct 10, 2011
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Chemokines (Greek -kinos, movement) are a family of small cytokines, or proteins secreted by cells. Their name is derived from their ability to induce directed chemotaxis in nearby responsive cells; they are chemotactic cytokines. Proteins are classified as chemokines according to shared structural characteristics such as small size (they are all approximately 8-10 kilodaltons in size), and the presence of four cysteine residues in conserved locations that are key to forming their 3-dimensional shape. However, these proteins have historically been known under several other names including the SIS family of cytokines, SIG family of cytokines, SCY family of cytokines, Platelet factor-4 superfamily or intercrines. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines are found in all vertebrates, some viruses and some bacteria, but none have been described for other invertebrates. These proteins exert their biological effects by interacting with G protein-linked transmembrane receptors called chemokine receptors, that are selectively found on the surfaces of their target cells.
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