Chemotherapy is one of the main therapeutic modalities for cancer patients. Chemotherapeutic drugs destroy cancer cells in the body, but patients frequently face side effects since the drugs do not selectively target cancer ...
Aug 31, 2023
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A new study suggests that the malaria drug hydroxychloroquine inhibits pathways that drive resistance to the chemotherapy agent cisplatin in head and neck cancers and restores tumor-killing effects of cisplatin in animal ...
Mar 14, 2022
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A new study led by University of California, Irvine (UCI) researchers identifies two ways in which APOBEC3A— a vital enzyme that is responsible for genetic changes resulting in a variety of cancers while protecting our ...
Aug 13, 2021
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A Ludwig Cancer Research study has found that inducing random chromosome instability (CIN) events in mice for as little as one week is enough to trigger harmful chromosomal patterns in cells that spur the formation of tumors.
Jul 16, 2021
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Chemotherapy is widely used to treat cancer patients. During the treatment, chemotherapeutic agents affect various biochemical processes to kill or reduce the growth of cancer cells, which divide uncontrollably in patients. ...
Jul 12, 2021
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Vanderbilt University researchers have reported the counterintuitive discovery that certain chemotherapeutic agents used to treat tumors can have the opposite effect of tissue overgrowth in normal, intact mammary glands, ...
Oct 16, 2020
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In their quest to destroy cancer cells, researchers are turning to combinational therapies more and more. Scientists from Germany and China have now combined a chemotherapeutic and photodynamic approach. All agents are encapsulated ...
Oct 13, 2020
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A team of researchers led by Worcester Polytechnic Institute (WPI) Provost Wole Soboyejo has identified targeted drugs that reduced the sizes of hard-to-treat breast cancer tumors in mice without inducing the toxic side effects ...
May 28, 2020
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Researchers at SMU's Center for Drug Discovery, Design and Delivery (CD4) have succeeded in lab testing the use of chemotherapy with a specific protein inhibitor so that the chemotherapeutic is better absorbed by drug-resistant ...
Jun 7, 2019
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An international team led by scientists at the National Institutes of Health is the first to discover a new way that cells fix an important and dangerous type of DNA damage known as a DNA-protein cross-link (DPC). The researchers ...
Oct 6, 2017
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