Diseases, Conditions, Syndromes

Ethiopia must do more to stop recurring chikungunya outbreaks

Ethiopia's second largest city, Dire Dawa, is dealing with a chikungunya fever outbreak. Around 20,000 cases of the mosquito-borne viral infection have been reported since the outbreak started in March 2019. This is the second ...

Diseases, Conditions, Syndromes

How chikungunya virus may cause chronic joint pain

A new method for permanently marking cells infected with chikungunya virus could reveal how the virus continues to cause joint pain for months to years after the initial infection, according to a study published August 29 ...

Diseases, Conditions, Syndromes

Study traces the origins of Chikungunya in Brazil

New evidence suggests that Chikungunya virus arrived in Brazil at least one year earlier than it was detected by public health surveillance systems. Scientists at the Center for Infection and Immunity (CII) at the Columbia ...

Diseases, Conditions, Syndromes

Chikungunya antibody set to enter clinical trial

A monoclonal antibody against the chikungunya virus developed by researchers at Vanderbilt University Medical Center is the first monoclonal antibody encoded by messenger RNA to enter a clinical trial.

Diseases, Conditions, Syndromes

Zika and Chikungunya viruses: Diagnostic pitfalls

Millions of people have contracted Zika and chikungunya virus infections since the outbreaks that have been striking Latin America since 2013. Zika-related malformations in newborns particularly warrant reliable diagnostics. ...

Diseases, Conditions, Syndromes

Toward vaccination against the chikungunya virus

A live vaccine genetically engineered from a common measles vaccine promises to be effective against the chikungunya virus. Such is the central finding of a recently completed Phase II trial now published in the prestigious ...

Diseases, Conditions, Syndromes

Sofosbuvir rids organism of chikungunya and yellow fever viruses

A study performed at the University of São Paulo's Biomedical Science Institute (ICB-USP) in Brazil shows that sofosbuvir, a drug used to treat chronic hepatitis C, is capable of eliminating chikungunya virus and yellow ...

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Chikungunya

Chikungunya (in the Makonde language "that which bends up") virus (CHIKV) is an insect-borne virus, of the genus Alphavirus, that is transmitted to humans by virus-carrying Aedes mosquitoes. There have been recent breakouts of CHIKV associated with severe illness. CHIKV infection causes an illness with symptoms similar to dengue fever, with an acute febrile phase of the illness lasting only two to five days, followed by a prolonged arthralgic disease that affects the joints of the extremities. The pain associated with CHIKV infection of the joints persists for weeks or months, or in some cases years.

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