Diseases, Conditions, Syndromes

Toward vaccination against the chikungunya virus

A live vaccine genetically engineered from a common measles vaccine promises to be effective against the chikungunya virus. Such is the central finding of a recently completed Phase II trial now published in the prestigious ...

Diseases, Conditions, Syndromes

Sofosbuvir rids organism of chikungunya and yellow fever viruses

A study performed at the University of São Paulo's Biomedical Science Institute (ICB-USP) in Brazil shows that sofosbuvir, a drug used to treat chronic hepatitis C, is capable of eliminating chikungunya virus and yellow ...

Diseases, Conditions, Syndromes

Taking the virus out of a mosquito's bite

They approach with the telltale sign—a high-pitched whine. It's a warning that you are a mosquito's next meal. But that mosquito might carry a virus, and now the virus is in you. Now, with the help of state-of-the-art technology, ...

Diseases, Conditions, Syndromes

Why chikungunya, other arthritis-causing viruses target joints

Chikungunya virus is a growing threat to the United States and other regions of the world as the mosquito that carries the virus expands its reach. Telltale symptoms of chikungunya infection are fever and joint pain that ...

Diseases, Conditions, Syndromes

Infection mechanism of Rift Valley fever virus identified

Rift Valley fever virus, transmitted by mosquitoes, is responsible for outbreaks in livestock in Africa and can also be fatal in humans. Scientists from the Institut Pasteur and the CNRS, working with the University of Göttingen, ...

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Chikungunya

Chikungunya (in the Makonde language "that which bends up") virus (CHIKV) is an insect-borne virus, of the genus Alphavirus, that is transmitted to humans by virus-carrying Aedes mosquitoes. There have been recent breakouts of CHIKV associated with severe illness. CHIKV infection causes an illness with symptoms similar to dengue fever, with an acute febrile phase of the illness lasting only two to five days, followed by a prolonged arthralgic disease that affects the joints of the extremities. The pain associated with CHIKV infection of the joints persists for weeks or months, or in some cases years.

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