Oncology & Cancer

Chlamydia knocks out the body's own cancer defence

Infections due to the sexually transmitted bacterium Chlamydia trachomatis often remain unnoticed. The pathogen is not only a common cause of female infertility; it is also suspected of increasing the risk of abdominal cancer. ...

Medical research

Molecular 'kiss of death' flags pathogens

Many bugs that make us sick—bacteria, viruses, fungi and parasites—hide out in our cells in protective little bubbles called vacuoles. To clear an infection, the immune system must recognize and destroy these vacuoles ...

Diseases, Conditions, Syndromes

New Chlamydia test shows type of infection

A new Chlamydia test can quickly and easily demonstrate the subtype (serovar) of the bacterium Chlamydia trachomatis a person is infected with. This has important clinical implications, because some Chlamydia subtypes, that ...

Diseases, Conditions, Syndromes

Study finds extragenital infections are underdiagnosed

An internship in summer 2018 under the auspices of UdeM's PREMIER program for excellence in medicine through introduction to research has culminated in the publication of an article in a scientific journal for undergraduate ...

Immunology

Blockade at the receptor

When chlamydia attacks the human body, the immune system activates. But the bacteria are adapted to defend themselves. Scientists from Würzburg have deciphered new details of their strategy.

Diseases, Conditions, Syndromes

Chlamydia utilizes Trojan horse tactics to infect cells

A novel mechanism has been identified in which Chlamydia trachomatis tricks host cells into taking up the bacteria. Researchers from University of California San Francisco, led by Joanne Engel, report their findings in the ...

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Chlamydia trachomatis

Chlamydia trachomatis, an obligate intracellular human pathogen, is one of three bacterial species in the genus Chlamydia. C. trachomatis is Gram-indeterminate (i.e. cannot be stained with the Gram stain); structurally the organism is Gram-negative. Identified in 1907, C. trachomatis was the first chlamydial agent discovered in humans.

C. trachomatis includes three human biovars: trachoma (serovars A, B, Ba or C), urethritis (serovars D-K), and lymphogranuloma venereum (LGV, serovars L1, 2 and 3). Many, but not all, C. trachomatis strains have an extrachromosomal plasmid.

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