Alzheimer's disease & dementia

Study hints at early sign of Alzheimer's degeneration

Researchers have moved one step closer to identifying targets for brain degeneration that occur decades before symptoms of Alzheimer's disease appear—a much sought-after clue that might open the door to early treatment.

Genetics

Sex-specific processes in schizophrenia and bipolar disorder

Recent studies have found a high genetic similarity of the psychiatric diseases schizophrenia and bipolar disorder, whose disease-specific changes in brain cells show an overlap of more than 70 percent. These changes affect ...

Medical research

Two groups of neurons identified in causing Leigh syndrome

Leigh syndrome affects one in every 40,000 newborns and is produced by deficits in the mitochondria, which produce the energy needed for cells to function correctly. Thus, cells with a high energy demand, such as the brain ...

Neuroscience

Surfing on calcium waves: A larva's journey to becoming a fly

Eric Carl, in his much-loved children's book The Very Hungry Caterpillar, documents the transformation of a gluttonous caterpillar into a beautiful butterfly. For a scientist, metamorphosis poses many unaddressed questions. ...

Alzheimer's disease & dementia

Pathway of Alzheimer's degeneration discovered

Scientists at the Montreal Neurological Institute and Hospital (The Neuro) of McGill University have used a unique approach to track brain degeneration in Alzheimer's disease, uncovering a pathway through which degeneration ...

Parkinson's & Movement disorders

New brainstem changes identified in Parkinson's disease

A pioneering study has found that patients with Parkinson's disease have more errors in the mitochondrial DNA within the brainstem, leading to increased cell death in that area.

Neuroscience

Mapping neurons to improve the treatment of Parkinson's

Because billions of neurons are packed into our brain, the neuronal circuits that are responsible for controlling our behaviors are by necessity highly intermingled. This tangled web makes it complicated for scientists to ...

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