Diseases, Conditions, Syndromes

'Humanized' liver in mice reveals roots of chronic diseases

Yale researchers have created a functional "humanized" liver in living mice that will help scientists find human-specific mechanisms for regulating cholesterol levels and potentially for treating chronic liver diseases afflicting ...

Addiction

How alcohol consumption contributes to chronic pain

Chronic alcohol consumption may make people more sensitive to pain through two different molecular mechanisms—one driven by alcohol intake and one by alcohol withdrawal. That is one new conclusion by scientists at Scripps ...

Medical research

Finding the best models for liver and kidney disease

In two separate studies, researchers at EPFL have carried out extensive tests to develop the best mouse models for studying kidney and liver diseases. The findings provide crucial insights into both conditions, and are expected ...

Diseases, Conditions, Syndromes

Why severe fatty liver leads to liver damage

In hepatic steatosis, hepatocytes "die," resulting in liver damage. Severe steatosis increases hepatocellular deaths, thus aggravating liver damage. The mechanism is unclear. Using mice, we show that mild steatosis causes ...

Diseases, Conditions, Syndromes

Q and A: Breaking down acute and chronic pancreatitis

I'm in my late 50s and was recently diagnosed with pancreatitis. My symptoms came on suddenly. My wife is concerned my symptoms may develop again, and she wants me to have testing to determine the cause. What are the testing ...

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