Diseases, Conditions, Syndromes

Cascade of events leading to prion disease described

Prion diseases are deadly neurodegenerative disorders in humans and animals that are characterized by misfolded forms of prion protein (PrP). Development of effective treatments has been hampered by the lack of good experimental ...

Medical research

Researchers show environment can neutralize lethal proteins

Botching a few folds might transform an origami cow into a deer or sheep. When cellular proteins do the same, they can trigger fatal neurodegenerative diseases that turn the brains of these mammals into dysfunctional sponges.

Diseases, Conditions, Syndromes

Kidney function trajectory starts in childhood, study finds

People who grew up in deprived socioeconomic conditions, or who were overweight in childhood, are more likely to have poorer kidney function in their 30s and 40s and are more at risk of developing chronic kidney disease as ...

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