Research provides insights into the pathology of keloid disease
A study in PNAS Nexus explores the microbiome of keloids, which are treatment-resistant raised scars.
Jul 31, 2024
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A study in PNAS Nexus explores the microbiome of keloids, which are treatment-resistant raised scars.
Jul 31, 2024
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Collagen, a major component of the extracellular matrix, plays a crucial role in tumor development. During the development of tumors ("tumorigenesis"), collagen fibers become linearized and densely deposited, hindering immune ...
May 23, 2024
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Eye diseases are extremely prevalent worldwide, with recent estimates suggesting that one-third of the global population suffers from some type of vision impairment. Given the high complexity of the human eye, the precise ...
May 16, 2024
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A healthy liver filters all the blood in your body, breaks down toxins and digests fats. It produces collagen to repair damaged cells when the liver is injured. However, a liver can produce too much collagen when an excess ...
Apr 26, 2024
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Researchers at the Center for Genomic Regulation in Barcelona and the University of Cologne in Germany have developed a new experimental strategy to tackle scarring and fibrosis. Experiments with patient-derived human cells ...
Apr 24, 2024
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Scientists at the NMI have unraveled the mode of action of collagen crosslinking in the treatment of corneal defects and the results open up new opportunities for the use of collagen in medicine.
Apr 19, 2024
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Doctors in the U.S. perform nearly 800,000 total knee replacements every year, but some estimates indicate that up to 10% of patients may emerge from surgery with a new problem: arthrofibrosis or excessive scarring that limits ...
Apr 16, 2024
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Researchers at Weill Cornell Medicine have discovered a protein called SEL1L that plays a critical role in clearing collagen from tissue, and that may be a therapeutic target to help prevent fibrosis, scar tissue that interferes ...
Mar 26, 2024
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Many people take collagen supplements, hoping to capture the fountain of youth. But can these products really reverse the aging process?
Mar 14, 2024
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Combined exposure of the skin to cigarette smoke and UV rays could lead to faster premature aging, according to a study by Université Laval and the Centre de recherche du CHU de Québec-Université Laval.
Feb 27, 2024
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Collagen /ˈkɒlədʒɨn/ is a group of naturally occurring proteins found in animals, especially in the flesh and connective tissues of mammals. It is the main component of connective tissue, and is the most abundant protein in mammals, making up about 25% to 35% of the whole-body protein content. Collagen, in the form of elongated fibrils, is mostly found in fibrous tissues such as tendon, ligament and skin, and is also abundant in cornea, cartilage, bone, blood vessels, the gut, and intervertebral disc. The fibroblast is the most common cell which creates collagen.
In muscle tissue, it serves as a major component of the endomysium. Collagen constitutes one to two percent of muscle tissue, and accounts for 6% of the weight of strong, tendinous muscles. Gelatin, which is used in food and industry, is collagen that has been irreversibly hydrolyzed.
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