Oncology & Cancer

Cancer cells 'talk' to their environment, and it talks back

Interactions between an animal cell and its environment, a fibrous network called the extracellular matrix, play a critical role in cell function, including growth and migration. But less understood is the mechanical force ...

Cardiology

3-D printing the human heart

A team of researchers from Carnegie Mellon University has published a paper in Science that details a new technique allowing anyone to 3-D bioprint tissue scaffolds out of collagen, the major structural protein in the human ...

Diseases, Conditions, Syndromes

Diabetes makes bones less bendable, more prone to fracture

Besides impairing cardiovascular and kidney function, Type 2 diabetes is known to be a risk factor for bone fractures – but exactly how diabetes makes bones more fragile has been unclear.

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Collagen

Collagen /ˈkɒlədʒɨn/ is a group of naturally occurring proteins found in animals, especially in the flesh and connective tissues of mammals. It is the main component of connective tissue, and is the most abundant protein in mammals, making up about 25% to 35% of the whole-body protein content. Collagen, in the form of elongated fibrils, is mostly found in fibrous tissues such as tendon, ligament and skin, and is also abundant in cornea, cartilage, bone, blood vessels, the gut, and intervertebral disc. The fibroblast is the most common cell which creates collagen.

In muscle tissue, it serves as a major component of the endomysium. Collagen constitutes one to two percent of muscle tissue, and accounts for 6% of the weight of strong, tendinous muscles. Gelatin, which is used in food and industry, is collagen that has been irreversibly hydrolyzed.

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