Neuroscience

Optimizing electrical stimulation therapies with machine learning

Like a pacemaker for the heart, nerve stimulation devices are implanted to send pulses of electricity to evoke activity in nerves throughout the body. These electrical stimulation devices have been used to treat and control ...

Neuroscience

How experience shapes neural connectivity in the brain

Our brain interprets visual information by combining what we see with what we already know. A study published in the journal Neuron, by researchers at the Champalimaud Foundation, reveals a mechanism for learning and storing ...

Computer simulation

A computer simulation, a computer model or a computational model is a computer program, or network of computers, that attempts to simulate an abstract model of a particular system. Computer simulations have become a useful part of mathematical modeling of many natural systems in physics (computational physics), chemistry and biology, human systems in economics, psychology, and social science and in the process of engineering new technology, to gain insight into the operation of those systems, or to observe their behavior.

Computer simulations vary from computer programs that run a few minutes, to network-based groups of computers running for hours, to ongoing simulations that run for days. The scale of events being simulated by computer simulations has far exceeded anything possible (or perhaps even imaginable) using the traditional paper-and-pencil mathematical modeling: over 10 years ago, a desert-battle simulation, of one force invading another, involved the modeling of 66,239 tanks, trucks and other vehicles on simulated terrain around Kuwait, using multiple supercomputers in the DoD High Performance Computer Modernization Program; a 1-billion-atom model of material deformation (2002); a 2.64-million-atom model of the complex maker of protein in all organisms, a ribosome, in 2005; and the Blue Brain project at EPFL (Switzerland), began in May 2005, to create the first computer simulation of the entire human brain, right down to the molecular level.

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