Researchers have revealed that the protein Toll-like receptor 7 (TLR7), usually associated with antiviral defense in the body, surprisingly, exacerbates lung conditions such as chronic obstructive pulmonary disease (COPD), ...
Nov 15, 2023
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Millions of Americans with tobacco-related lung disease have symptoms that do not fit any existing tobacco-related disease criteria—including the most common of those, chronic obstructive pulmonary disease (COPD)—according ...
Aug 1, 2023
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A retrospective analysis of patient data from the COPDGene study suggests that targeting mucus plugs could help prevent deaths from chronic obstructive pulmonary disease—the fourth leading cause of death in the United States
May 21, 2023
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A team of medical researchers, engineers and computer scientists affiliated with multiple institutions across the U.S. has found that machine learning technology can help doctors predict which patients are at risk of developing ...
A new tool shows promise in helping primary care physicians identify adults with undiagnosed chronic obstructive pulmonary disease (COPD), according to research published in JAMA. More than 15 million Americans have been ...
Feb 14, 2023
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Chronic obstructive pulmonary disease (COPD) is the most common chronic respiratory disease worldwide and the third leading cause of death. In Germany, about 10% of the population is affected. Fatigue, coughing and persistent ...
Sep 27, 2022
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A team of international scientists led by the Nanyang Technological University, Singapore (NTU Singapore) has discovered that Neisseria—a genus of bacteria that lives in the human body—is not as harmless as previously ...
Sep 14, 2022
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NUS scientists have discovered a novel property of a protein found in human lungs that could lead to the development of biologic drugs to treat chronic obstructive pulmonary disease (COPD), a debilitating, progressive lung ...
Apr 25, 2022
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A team of researchers from the Netherlands, Germany and the U.S. reports that two drugs show promise in rejuvenating lung epithelial progenitor cells damaged by chronic obstructive pulmonary disease (COPD). In their study, ...
Researchers at Baylor College of Medicine, Yale University and other institutions have identified previously unrecognized changes in gene expression and cellular interactions in distinct cell populations in chronic obstructive ...
Jan 27, 2022
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Chronic obstructive pulmonary disease (COPD) refers to chronic bronchitis and emphysema, a pair of two commonly co-existing diseases of the lungs in which the airways become narrowed. This leads to a limitation of the flow of air to and from the lungs causing shortness of breath. In contrast to asthma, the limitation of airflow is poorly reversible and usually gets progressively worse over time.
COPD is caused by noxious particles or gas, most commonly from smoking, which trigger an abnormal inflammatory response in the lung. The inflammatory response in the larger airways is known as chronic bronchitis, which is diagnosed clinically when people regularly cough up sputum. In the alveoli, the inflammatory response causes destruction of the tissues of the lung, a process known as emphysema. The natural course of COPD is characterized by occasional sudden worsenings of symptoms called acute exacerbations, most of which are caused by infections or air pollution.
The diagnosis of COPD requires lung function tests. Important management strategies are smoking cessation, vaccinations, rehabilitation, and drug therapy (often using inhalers). Some patients go on to requiring long-term oxygen therapy or lung transplantation.
Worldwide, COPD ranked sixth as the cause of death in 1990. It is projected to be the third leading cause of death worldwide by 2020 due to an increase in smoking rates and demographic changes in many countries. COPD is the 4th leading cause of death in the U.S., and the economic burden of COPD in the U.S. in 2007 was $42.6 billion in health care costs and lost productivity.
COPD is also known as chronic obstructive lung disease (COLD), chronic obstructive airway disease (COAD), chronic airflow limitation (CAL) and chronic obstructive respiratory disease.
This text uses material from Wikipedia, licensed under CC BY-SA
