It is assumed that the brain has homeostatic mechanisms to prevent the depletion of cellular energy, required for all cellular activities. For example, the blood flow increases, and oxygen and glucose are actively delivered ...
Oct 7, 2020
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Transcription factor Heat Shock Factor 1 (Hsf1), which the developing brain releases to shield the vital organ from the ravages of environmental stress, actually can contribute to impairing the embryonic brain when too much ...
May 2, 2017
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Real estate agents emphasize location, location, and – once more for good measure – location. It's the same in a developing brain, where billions of neurons vie for premium property to make connections. Neurons that stake ...
Oct 31, 2013
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Scientists have found that the outer cortex of the mammalian brain is able to maintain control over all the external inputs it receives because of how its nerve networks are organized into interconnected but independently ...
Sep 20, 2023
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The gene mutation that causes Huntington's disease appears in every cell in the body, yet kills only two types of brain cells. Why? UCLA scientists used a unique approach to switch the gene off in individual brain regions ...
Apr 28, 2014
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Researchers from King's College London have discovered that neuronal activity can stimulate tau release from healthy neurons in the absence of cell death. The results published by Diane Hanger and her colleagues in EMBO reports ...
Feb 15, 2013
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The causes of autism spectrum disorder (ASD) are diverse and to some extent, unknown. But without doubt, they are complex, layered and deeply nuanced. In a study published January 17, 2019 in Translational Psychiatry, researchers ...
Jan 30, 2019
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Researchers at the ULB – IRIBHM and ULB Neuroscience Institute – have tested the therapeutic potential of cortical neurons generated at the laboratory, by transplantation in the brains of adult mice. Their research is ...
Mar 6, 2015
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Epilepsy, one of the most common neurological disorders, is characterized by the spontaneous repetition of seizures caused by the hyperactivity of a group of neurons in the brain. Could we therefore reduce neuronal hyperactivity, ...
Mar 24, 2022
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Researchers at the UNC School of Medicine have found that the protein glycogen synthase kinase-3, or GSK-3, is crucial for proper brain development early in life, a surprising finding considering that drug companies are searching ...
Jul 30, 2014
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