An old antibiotic may provide much-needed protection against multi-drug resistant bacterial infections, according to a new study published May 16 in the open access journal PLOS Biology by James Kirby of Harvard Medical School, ...
May 16, 2023
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171
SPOP is the most mutated protein in prostate cancer and plays a role in endometrial, uterine and other cancers. Despite this importance, how SPOP mutations drive cancer has been incompletely understood. Scientists at St. ...
Jan 23, 2023
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31
After Alzheimer's, Parkinson's is the most common neurodegenerative disease in the world. More than six million people worldwide suffer from it. In this disease, alpha-synuclein proteins form thread-like structures called ...
Nov 15, 2022
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980
Researchers at the University of British Columbia have discovered a key vulnerability across all major variants of the SARS-CoV-2 virus, including the recently emerged BA.1 and BA.2 Omicron subvariants.
Aug 18, 2022
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98
Using a state-of-the-art method, researchers at DZNE and the University of Texas have succeeded for the first time at unraveling the effects of autoimmune antibodies that are directed against the brain in detail at the atomic ...
Jul 8, 2022
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58
Researchers have worked out how to successfully switch off a key pathway of nerve fiber breakdown in debilitating neurodegenerative disorders such as Parkinson's disease, traumatic brain injury and glaucoma.
Mar 28, 2022
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96
Researchers at the Francis Crick Institute have identified structural changes in COVID-19 variants which provide clues to how the virus evolved to have greater levels of infectivity.
Mar 4, 2022
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40
Using advanced imaging technology, Mayo Clinic scientists have provided an unprecedented understanding of the BRCA1-BARD1 protein complex, which is often mutated in patients with breast or ovarian cancer. Their paper, published ...
Jul 28, 2021
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297
Combining structural biology and computation, a Duke-led team of researchers has identified how multiple mutations on the SARS-CoV-2 spike protein independently create variants that are more transmissible and potentially ...
Jun 29, 2021
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28
A Griffith University-led research team has discovered how a therapeutic target common among debilitating neurodegenerative disorders is activated, which could help accelerate drug development.
Mar 3, 2021
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48
