Medical research

Scientists reverse deadly impacts of asthma in mice

Mucus in the lungs can be fatal for asthma patients, but scientists at the University of Colorado Anschutz Medical Campus have broken up those secretions at the molecular level and reversed their often deadly impacts.

Diseases, Conditions, Syndromes

Machine learning comes of age in cystic fibrosis

World-leading AI technology developed by the Cambridge Centre for AI in Medicine and their colleagues offers a glimpse of the future of precision medicine, and unprecedented predictive power to clinicians caring for individuals ...

Obstetrics & gynaecology

Baby girl born from embryo frozen for 27 years

(HealthDay)—A baby girl born in Tennessee from a 27-year frozen embryo broke the record for the longest-frozen embryo to result in a live birth, which was held by her older sister, Emma.

Diseases, Conditions, Syndromes

Understanding lung infections in patients with cystic fibrosis

Staphylococcus aureus (which includes MRSA) is the most prevalent organism isolated from the airways of children with cystic fibrosis (CF), and is treated using antibiotics, but its role in lung disease is poorly understood.

Medical research

Researchers create human airway stem cells from patients' cells

For the first time, researchers have successfully created airway basal stem cells in vitro from induced pluripotent stem cells by reprogramming blood cells taken from patients. Given that airway basal cells are defined as ...

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Cystic fibrosis

Cystic fibrosis (also known as CF, mucovoidosis, or mucoviscidosis) is a genetic disorder known to be an inherited disease of the secretory glands, including the glands that make mucus and sweat.

The hallmarks of cystic fibrosis are salty tasting skin, normal appetite but poor growth and poor weight gain, excess mucus production, and coughing/shortness of breath. Males can be infertile due to the condition Congenital absence of the vas deferens. Often, symptoms of CF appear in infancy and childhood. Meconium ileus is a typical finding in newborn babies with CF.

Although technically a rare disease, cystic fibrosis is ranked as one of the most widespread life-shortening genetic diseases. It is most common among nations in the Western world; one in twenty-two people of Mediterranean descent is a carrier of one gene for CF, making it the most common genetic disease in these populations.[citation needed] An exception is Finland, where only one in 80 people carry a CF mutation. In the United States, 1 in 4,000 children are born with CF. In 1997, about 1 in 3,300 caucasian children in the United States was born with cystic fibrosis. In contrast, only 1 in 15,000 African American children suffered from cystic fibrosis, and in Asian Americans the rate was even lower at 1 in 32,000.

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