Scientists have discovered that cervical cancer can be divided into two distinct molecular subgroups—one far more aggressive than the other—as part of the largest "omics" study of its kind, led by researchers at UCL and ...
Oct 21, 2022
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A Ludwig Cancer Research study has identified a combination of three existing drugs that significantly extends survival in mouse models of the lethal brain cancer glioblastoma multiforme (GBM).
Sep 20, 2022
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Pancreatic cysts have gained substantial attention in recent years because they represent one of the only precursors of pancreatic cancer identifiable through radiologic imaging. Although most of these cysts, also known as ...
Sep 1, 2022
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T cells are usually good at eliminating diseased cells, but they seem to fail when it comes to tumor cells. In JCI Insight, MDC teams led by Armin Rehm and Uta Höpken describe what inhibits this immune function, and how ...
Jun 13, 2022
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Researchers have successfully treated type 1 diabetes in mice using pancreatic beta-cell, target-specific, chimeric antigen-receptor (CAR) regulatory T cells (Tregs), and demonstrated the feasibility of their approach to ...
Jun 13, 2022
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Biomarkers are often used during the management of cancer to guide treatment decisions and predict patient outcomes. However, it is often difficult to identify appropriate biomarkers that that can be consistently reproduced ...
May 18, 2022
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Dihydroartemisinin (DHA), an active metabolite of artemisinin and the most potent anti-malaria drug, is also used to treat autoimmune diseases such as systemic lupus erythematosus (SLE) and psoriasis. Since the first report ...
Mar 28, 2022
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Scientists have created a pipeline for identifying, prioritizing and evaluating potential tumor antigens for the fast generation of cancer vaccines, according to a report published today in eLife.
Mar 22, 2022
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In the clinical care of people living with HIV, various types of blood cells are routinely counted to assess the immune system, among them CD4+ cells, or T helper cells, and CD8+ cells, or cytotoxic T cells.
Mar 18, 2022
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People who gained immunity—either through vaccination or exposure—against the original strain of SARS-CoV-2, the virus that causes COVID-19, also are likely to have some protection against the pathogen's Omicron variant. ...
Mar 11, 2022
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