For the first time, researchers have demonstrated that the response of natural killer (NK) cells is detrimental to glioblastoma virotherapy, a novel way of treating malignant brain cancer by injecting a virus into the tumor. ...
Dec 4, 2012
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Humans encounter innumerable pathogenic bacteria, viruses and other microbes in their day-to-day activities. While infections from some pathogens can be easily cleared by the innate immune system, others can evade this first ...
May 11, 2023
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Researchers from the Research Programme in Biomedical Informatics (GRIB) from the IMIM (Hospital del Mar Research Institute) and the Pompeu Fabra University (UPF) have identified 115 proteins in silico (via computer simulation) ...
Apr 26, 2012
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A novel, targeted approach to chemotherapy that makes ovarian cancer cells more susceptible to the cytotoxic effects of an antitumor drug may offer a safer, more effective treatment option for this often deadly form of cancer. ...
May 29, 2013
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Dihydroartemisinin (DHA), an active metabolite of artemisinin and the most potent anti-malaria drug, is also used to treat autoimmune diseases such as systemic lupus erythematosus (SLE) and psoriasis. Since the first report ...
Mar 28, 2022
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New research suggests that targeting autoimmune inflammation associated with amyotrophic lateral sclerosis (ALS) using two drugs, one of them already approved for multiple sclerosis, could be a promising approach for treatment.
Jul 13, 2023
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The magic to killing cancer cells might not be in the bullet, but in the gunpowder that accompanies it, according to researchers at the University of Pittsburgh Cancer Institute (UPCI), partner with UPMC CancerCenter. Instead ...
Nov 15, 2013
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There are plenty of effective anticancer agents around. The problem is that, very often, they cannot gain access to all the cells in solid tumors. A new gene delivery vehicle may provide a way of making tracks to the heart ...
Nov 14, 2012
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Superantigens are molecules that can stimulate a strong immune response by activating a large number of cytotoxic T cells, which are white blood cells that can eliminate tumor cells. One example of a superantigen is staphylococcal ...
Aug 14, 2023
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Contrary to what was previously believed, the immune system's cancer-killing T cells are more effective in a tumour's anoxic environment when they have access to growth factor VEGF-A. In a study from Karolinska Institutet ...
Nov 13, 2017
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