Some hereditary genetic defects cause an exaggerated immune response that can be fatal. Using the CRISPR-Cas9 gene-editing tool, such defects can be corrected, thus normalizing the immune response, as researchers led by Klaus ...
Feb 2, 2024
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Millions of people across the world have been infected with SARS-CoV-2, the virus that causes COVID-19. Countries are also now embarking on massive vaccination campaigns to control the virus and protect their most vulnerable ...
Jan 12, 2021
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A new study from SUNY Downstate Medical Center in Brooklyn, New York, shows that MAL3-101, a recently developed inhibitor of the heat shock protein 70 (Hsp70), appears to have potent anti-tumor effects on multiple myeloma, ...
Jan 9, 2012
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Researchers in China have discovered how brain cancer cells increase production of a key protein that allows them to evade the body's immune system. The study, which will be published August 27 in the Journal of Experimental ...
Aug 27, 2020
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People who gained immunity—either through vaccination or exposure—against the original strain of SARS-CoV-2, the virus that causes COVID-19, also are likely to have some protection against the pathogen's Omicron variant. ...
Mar 11, 2022
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Immune cells called "killer T cells," also known as cytotoxic or cytolytic CD8 T cells, normally stay in the bloodstream and do not enter organs and other tissues, according to a new study from scientists in the Perelman ...
Dec 11, 2020
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The use of immunotherapy to treat cancer is celebrating its first successes – but there are still many knowledge gaps in the underlying mechanisms of action. In a study of mice with soft tissue tumors, ETH researchers have ...
Jun 2, 2017
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Short bursts of radiation therapy dramatically enhanced the efficiency of targeting glioblastomas with natural nanoparticle-based immunotherapy, thus suppressing growth of the deadly tumor, inducing anti-tumor immunity and ...
Jan 31, 2022
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Researchers have successfully treated type 1 diabetes in mice using pancreatic beta-cell, target-specific, chimeric antigen-receptor (CAR) regulatory T cells (Tregs), and demonstrated the feasibility of their approach to ...
Jun 13, 2022
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Many questions about how exposure to SARS-CoV-2 by infection or immunization might result in long-term protective immunity remain unanswered. Onur Boyman, head of the Department of Immunology, and his research team at the ...
Feb 2, 2022
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