A Ludwig Cancer Research study has identified a combination of three existing drugs that significantly extends survival in mouse models of the lethal brain cancer glioblastoma multiforme (GBM).
Sep 20, 2022
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Pancreatic cysts have gained substantial attention in recent years because they represent one of the only precursors of pancreatic cancer identifiable through radiologic imaging. Although most of these cysts, also known as ...
Sep 1, 2022
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T cells are usually good at eliminating diseased cells, but they seem to fail when it comes to tumor cells. In JCI Insight, MDC teams led by Armin Rehm and Uta Höpken describe what inhibits this immune function, and how ...
Jun 13, 2022
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Researchers have successfully treated type 1 diabetes in mice using pancreatic beta-cell, target-specific, chimeric antigen-receptor (CAR) regulatory T cells (Tregs), and demonstrated the feasibility of their approach to ...
Jun 13, 2022
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Often undetected until it has progressed to an advanced stage, pancreatic ductal adenocarcinoma (PDAC) is a lethal cancer. The K-Ras mutant pancreatic cancer is one of the most common types. At present, there are no effective ...
Jun 6, 2022
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Biomarkers are often used during the management of cancer to guide treatment decisions and predict patient outcomes. However, it is often difficult to identify appropriate biomarkers that that can be consistently reproduced ...
May 18, 2022
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According to new research from Boston Medical Center, the antibody function known as antibody dependent cellular cytotoxicity (ADCC) and the ADCC sensitivity of HIV strains may influence the transmission of HIV from mother ...
Apr 20, 2022
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Dihydroartemisinin (DHA), an active metabolite of artemisinin and the most potent anti-malaria drug, is also used to treat autoimmune diseases such as systemic lupus erythematosus (SLE) and psoriasis. Since the first report ...
Mar 28, 2022
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Scientists have created a pipeline for identifying, prioritizing and evaluating potential tumor antigens for the fast generation of cancer vaccines, according to a report published today in eLife.
Mar 22, 2022
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In the clinical care of people living with HIV, various types of blood cells are routinely counted to assess the immune system, among them CD4+ cells, or T helper cells, and CD8+ cells, or cytotoxic T cells.
Mar 18, 2022
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