Oncology & Cancer

Ruptures in cell nuclei promotes tumor invasion in breast cancer

When cells multiply and migrate, they can be compressed and their nucleus may break open. This phenomenon causes DNA damage. Scientists from the CNRS, Institut Curie and INSERM have now shown that this facilitates the spread ...

Medical research

A specific subset of immune cells that mitigates kidney damage

The immune system is highly complex. For example, a particular class of cells called mononuclear phagocytes (MNPs) plays important roles in the uptake and disposal of damaged cells, the elimination of invasive pathogens and ...

Medical research

'Good cholesterol' may protect liver

The body's so-called good cholesterol may be even better than we realize. New research from Washington University School of Medicine in St. Louis suggests that one type of high-density lipoprotein (HDL) has a previously unknown ...

Medical research

3D 'assembloid' shows how SARS-CoV-2 infects brain cells

Researchers at University of California San Diego School of Medicine and Rady Children's Institute for Genomic Medicine have produced a stem cell model that demonstrates a potential route of entry of SARS-CoV-2, the virus ...

Diseases, Conditions, Syndromes

Immune cells promote proinflammatory fatty liver disease

A particular type of dendritic cell is responsible for the tissue damage that occurs in non-alcoholic steatohepatits (NASH) in mice and humans. The dendritic cells cause aggressive, proinflammatory behavior in T cells, as ...

Medical research

Repairing nerves requires prods of protein

When there's damage in the body, our cells call for help. UConn brain researchers just found a new way cells do this—like in the old AT&T ad campaign, they reach out and touch someone.

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