In experiments with human colon cancer cells and mice, a team led by scientists at the Johns Hopkins Kimmel Cancer Center say they have evidence that cancer arises when a normal part of cells' machinery generally used to ...
May 8, 2017
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About half of all cancer patients have a mutation in a gene called p53, which allows tumors to survive and continue growing even after chemotherapy severely damages their DNA.
Nov 14, 2013
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Fanconi anemia is a rare genetic disease characterized by hematologic symptoms that include low platelet count and unusually large red blood cells. Mutations in nearly 20 genes have been identified as causative for Fanconi ...
Jul 10, 2017
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Risk for melanoma, the most deadly skin cancer, can be estimated long before detection of any suspicious moles, according to a UC San Francisco scientist who led a new study to detect DNA mutations in individual skin cells.
Oct 7, 2020
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Researchers have created a huge resource for investigating the biological mechanisms that cause cancer. The scientists from the Wellcome Sanger Institute and their collaborators identified which patterns of DNA damage—mutational ...
Mar 7, 2019
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Burkholderia pseudomallei is a bacterium in the soil that causes melioidosis, a tropical disease with high morbidity and mortality. Recently, researchers at the NUS Yong Loo Lin School of Medicine discovered that Burkholderia ...
Jul 8, 2020
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Scientists at the IRCM and the University of Montreal discovered a mechanism that promotes the progression of medulloblastoma, the most common brain tumour found in children. The team, led by Frédéric Charron, PhD, found ...
Oct 29, 2014
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Researchers have discovered a novel mechanism in a combination drug therapy that shows potential as a new approach for treating acute myeloid leukemia (AML) and many other cancers. When combined, these agents cause interactions ...
Oct 10, 2016
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As different cells penetrate through tight, confining spaces within tissue, they often deform, causing their nuclei to rupture under the associated stress. A new study led by Cornell University engineers finds that cancer ...
Mar 24, 2016
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(Medical Xpress)—A new discovery by Cornell researchers may lead to therapies that allow women who are made infertile by radiation or chemotherapy treatments to have children.
Jan 30, 2014
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